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Covid-19 vaccine booster dose efficacy against the new variant Omicron

Page with all the IPSEs stored in the archive related to the Context Covid-19 vaccine booster dose efficacy against the new variant Omicron.
The IPSEs are presented in chronological order based on when the IPSEs have been pronounced.

Chaand Nagpaul
Chaand Nagpaul

“What we know now of course is that the patients, people who are becoming seriously ill, who are being hospitalised, are those who have not been vaccinated and those who have not had their boosters.”

author
Chair of the British Medical Association
24 Dec 2021 3 4
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Boris Johnson
Boris Johnson

“Though the time for buying presents is theoretically running out, there is still a wonderful thing you can give your family and the whole country and that is to get that jab, whether it is your first or your second or your booster. Omicron is surging. [And] we all know we must together try to stop the spread of this new variant - we must test ourselves and take extra care when meeting elderly or vulnerable relatives.”

author
UK Prime Minister
24 Dec 2021 4 4
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Soumya Swaminathan
Soumya Swaminathan

“Everybody wants to know about the boosters, when it's needed, how often it's going to be needed and so on. There are many factors that can influence this. One is the type of vaccine. We know that each vaccine has a slightly different performance and longer follow up is telling us the efficacy of the vaccines, particularly in preventing severe disease but also in preventing infection. The other big variable of course is, the variants of the virus that we are seeing. And we've seen that different variants have different abilities to be neutralized by the antibodies, or be able to overcome the immune response, like Omicron seems to be doing because of the mutations it has it seems to be pretty good at evading immune responses. The third factor of course is the biology of the individual, the age of the person, how strong the immune system is, whether there are other underlying illnesses which impact the immune system. And therefore when we make recommendations for a course of vaccination, we have to take into consideration all of these factors. There is some data now to show that there is a slippage in the protection due to the different vaccines at about six months or so, particularly for protection from infection, less so for protection from disease; they are still performing at 80%. But with Omicron again, the initial data coming in obviously showing that Omicron is very successfully able to evade immune responses and therefore needs higher levels of antibodies. For now we believe that boosters may be needed for people who have weaker immune systems, the older individuals, the more vulnerable people and whether a third dose of the vaccine is going to be it, or whether they are going to be need for additional vaccines like influenza every year, every couple of years, it's too early to say and we need to really follow the science on that.”

author
World Health Organization’s (WHO) chief scientist
20 Dec 2021 5 3
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Peter Jüni
Peter Jüni

“It's not a recipe against the current tidal wave that Ontario is starting to face already, and other provinces will follow. We invest with the booster so that when we loosen restrictions again … we start to see protections through the boosters. That's the idea. We need interventions to blunt the wave so that we have a bit more time so that … we are able to roll [boosters] out and that they are able to start to develop their effectiveness.”

Cbc

author
Director of Ontario's COVID-19 Science Advisory Table
19 Dec 2021 4 5
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Sandra Ciesek
Sandra Ciesek

“A booster jab will pump up your protection to 70-75% and it will also reduce your risk of a severe infection but that could also lend you a false sense of security. While it is important to get the unvaccinated vaccinated, first jabs would not be enough to fight off omicron. It takes many weeks for the immune system to develop a defense. The virus moves faster than that.”

Dw

author
Director of the Institute of Medical Virology at the University Hospital Frankfurt
17 Dec 2021 7 6
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Jeremy Kamil
Jeremy Kamil

“These authors found Omicron replicates fantastically well - even far better than either Delta or the original virus - in bronchial tissue. This could in some ways contribute to an advantage in spread/transmission between people. Of course, a huge component of Omicron's transmissibility in real life is going to be its potential to escape neutralising antibodies that protect against infect in the first place. It's very likely spreading well even between vaccinated people, especially those who haven't recently gotten a booster shot.”

author
Associate professor of microbiology and immunology at Louisiana State University Health Shreveport
15 Dec 2021 8 3
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Albert Bourla
Albert Bourla

“Although two doses of the vaccine may still offer protection against severe disease caused by the Omicron strain, it's clear from these preliminary data that protection is maximised with a third dose of our vaccine. Ensuring as many people as possible are fully vaccinated with the first two dose series and a booster remains the best course of action to prevent the spread of COVID-19.”

author
Pfizer chairman and chief executive
08 Dec 2021 6 3
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Ugur Sahin
Ugur Sahin

“Our message is: Don't freak out, the plan remains the same: Speed up the administration of a third booster shot. Our belief [that the vaccines work against Omicron] is rooted in science: If a virus achieves immune escape, it achieves it against antibodies, but there is the second level of immune response that protects from severe disease-the T-cells.”

author
Chief executive of Germany’s BioNTech
30 Nov 2021 6 4
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Joe Biden
Joe Biden

“This variant is a cause for concern, not a cause for panic. If you are vaccinated, but still worried about the new variant, get your booster. If you aren't vaccinated, get that shot. Go get that first shot. We'll fight this variant with scientific and knowledgeable actions and speed, not chaos and confusion. The point of the [travel] restriction is to give us time to get people vaccinated.”

author
President of the United States
29 Nov 2021 6 4
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Francis Collins
Francis Collins

“We expect that most likely the current vaccines will be sufficient to provide protection. And especially the boosters will give that additional layer of protection.”

author
Director of the National Institutes of Health
28 Nov 2021 4 3
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